Simparica Trio for Dogs
Simparica Trio for dogs: one monthly chew for fleas, ticks, heartworm and worms. Shop by weight, no vet prescription.
About Simparica Trio for Dogs
Monthly Chewable Parasite Protection without vet prescription
Simparica Trio is a monthly chewable tablet for dogs that combines broad parasite protection into a single liver-flavored chew. At Smartway Pet Supplies, you can shop the full Simparica Trio range by weight — no vet prescription required — and get genuine product shipped fast to the USA and Canada.
Each chewable tablet is designed to protect against fleas, ticks, heartworm, roundworms, and hookworms in one convenient monthly dose. For dog owners who want all-in-one coverage without managing multiple separate treatments, Simparica Trio is one of the most practical options available.
What Does Simparica Trio Cover?
Simparica Trio chewable tablets for dogs provide broad monthly protection across five major parasite categories:
- Fleas — Begins killing fleas within hours of the first dose. With consistent monthly use, it helps control flea infestations and breaks the flea life cycle in your home environment.
- Ticks — Provides protection against six tick species including the American dog tick, brown dog tick, lone star tick, Gulf Coast tick, black-legged (deer) tick, and Asian longhorned tick. Ticks can carry serious diseases, making consistent monthly protection especially important for dogs that spend time outdoors.
- Heartworm Prevention — Eliminates immature heartworm larvae before they develop. Heartworm is spread by mosquitoes and can become a serious, life-threatening condition if left untreated.
- Roundworms & Hookworms — Treats and controls common intestinal worms in a single chew, removing the need for a separate monthly worming product.
Active Ingredients in Simparica Trio
Simparica Trio contains three active ingredients that work together to deliver its broad coverage:
- Sarolaner — An isoxazoline class compound that kills fleas and ticks by targeting their nervous systems
- Moxidectin — Prevents heartworm disease and treats intestinal parasites
- Pyrantel — Treats and controls roundworms and hookworms
Simparica Trio is an Australian-registered veterinary product suitable for dogs and puppies 8 weeks of age and older, weighing at least 2.8 lbs (1.3 kg).
Simparica Trio Sizes & Pricing — Choose by Dog Weight
Simparica Trio chewable tablets are available in six weight-based sizes. Always choose the pack that matches your dog's current body weight. Using the correct size is essential for proper monthly dosing.
| Pack Colour | Dog Size | Weight Range | Price (from) |
|---|---|---|---|
| Yellow | Puppies | 2.8 – 5.5 lbs (1.3 – 2.5 kg) | $59 |
| Purple | Extra Small Dogs | 5.6 – 11 lbs (2.6 – 5 kg) | $60 |
| Orange | Small Dogs | 11.1 – 22 lbs (5.1 – 10 kg) | $78 |
| Blue | Medium Dogs | 22.1 – 44 lbs (10.1 – 20 kg) | $83 |
| Green | Large Dogs | 44.3 – 88 lbs (20.1 – 40 kg) | $87 |
| Red | Extra Large Dogs | 88.1 – 132 lbs (40.1 – 60 kg) | $94 |
If your dog is close to a weight cutoff, weigh them carefully before ordering. Each size links directly to its matching product page so you can shop the right Simparica Trio chewy for your dog's weight without any guesswork. A 6-chew pack costs less per dose than two 3-chew packs, so it's the better value if you're stocking up.
Why Dog Owners Choose Simparica Trio
The main reason dog owners choose a Simparica Trio chewable tablet over other monthly treatments is convenience. Instead of using separate products for flea control, tick prevention, heartworm, and intestinal worms, one monthly chew covers all of those needs.
Key reasons customers buy Simparica Trio at Smartway Pet Supplies:
- All-in-one monthly parasite coverage in a single chew
- Covers fleas, ticks (six species including American dog tick, brown dog tick, lone star tick, Gulf Coast tick, black-legged deer tick, and Asian longhorned tick), heartworm, roundworms, and hookworms
- Clinically tested and trusted by pet owners worldwide
- Liver-flavored chewable tablet most dogs take willingly
- No messy topical application
- Weight-based sizing from puppies through to extra large breeds
- Available without a vet prescription at Smartway Pet Supplies
- Competitive pricing with free standard shipping on orders over $125
Customers comparing options such as NexGard, Bravecto for Dogs, or other monthly treatments will find Simparica Trio stands out because of the combination of flea, tick, heartworm, and intestinal worm coverage in one product. For those looking for Simparica Trio best price with genuine product and reliable delivery, Smartway Pet Supplies is a trusted option.
Important Safety Information & Caution in Dogs
Simparica Trio is Australian-registered and widely used. However, as with all isoxazoline class treatments, there are important safety considerations to be aware of before use.
Use in puppies and older dogs:
Simparica Trio is approved for puppies 8 weeks of age and older. For dogs of advanced age and older dogs with pre-existing health conditions, speak with your veterinarian before starting any new parasite treatment.
Neurologic adverse reactions:
The isoxazoline class of parasiticides, which includes Sarolaner, has been associated with neurologic adverse reactions including tremors, ataxia and seizures in some dogs, particularly those with pre-existing neurological conditions. These reactions are considered rare but are important to be aware of. If your dog has a history of seizures or neurological issues, consult your vet before use.
General caution in dogs:
- Use only in dogs — not for use in cats or other animals
- Always match the correct pack size to your dog's current body weight
- Do not use in dogs under 8 weeks of age or under the minimum weight for the smallest pack
- If adverse reactions occur after dosing, contact your veterinarian promptly
Genuine Simparica Trio — Sourced from Reputable Distributors
Smartway Pet Supplies sells only 100% genuine, brand-name products in original manufacturer packaging. We source from reputable wholesalers so you can shop with confidence.
Alongside Simparica Trio, we carry other leading parasite prevention brands including:
Helpful Guides
Learn more about Simparica Trio and how it compares to other parasite treatments:
- How Long Does Simparica Trio Take to Work?
- NexGard Spectra vs Simparica Trio: The Full Comparison
- Bravecto vs Simparica Trio: Which Is Better?
- Can You Buy Simparica Trio Without a Vet Prescription?
- Puppy Parasite Prevention Guide
Shop More Dog Parasite Treatments at Smartway
Browse our full range of genuine dog health products:
Frequently asked questions
What is Simparica Trio for dogs used for?
It is a monthly chewable tablet used to protect against fleas and ticks, prevent heartworm disease, and treat and control roundworms and hookworms.
How often should I give Simparica Trio?
One chew every 30 days.
Is Simparica Trio a registered veterinary product?
Yes. Simparica Trio is Australian-registered and suitable for dogs and puppies 8 weeks of age and older, weighing at least 2.8 lbs (1.25 kg).
What active ingredients does Simparica Trio contain?
The three active ingredients are Sarolaner (isoxazoline class), Moxidectin, and Pyrantel. Together they provide broad-spectrum parasite protection in one monthly chew.
Which tick species does Simparica Trio protect against?
It protects against six tick species: the American dog tick, brown dog tick, lone star tick, Gulf Coast tick, black-legged (deer) tick, and Asian longhorned tick, including the tick species that transmits Lyme disease.
How quickly does Simparica Trio start working?
Simparica Trio begins killing fleas within hours of the first dose. Consistent monthly use is important to maintain protection, particularly for heartworm prevention.
Does Simparica Trio prevent heartworm?
Yes. Each monthly dose provides heartworm prevention.
Can puppies take Simparica Trio?
Yes. It is suitable for puppies 8 weeks of age and older, provided they meet the minimum weight requirement of 2.8 lbs (1.25 kg).
Are there neurologic risks with Simparica Trio?
Sarolaner belongs to the isoxazoline class, which has been associated with neurologic adverse reactions including tremors, ataxia and seizures in rare cases. Dogs with a history of seizures or neurological conditions should only use this product under veterinary guidance.
Are there other side effects?
Most dogs tolerate it well; mild digestive upset, itching, or lethargy can occur. Consult your vet if symptoms persist.
Can I give Simparica Trio with other medications?
Often yes, but check with your veterinarian if your dog is on other treatments.
What if my dog vomits after dosing?
If vomiting occurs within a few hours, re-dose with another chew; contact your vet if it continues.
What if I miss a dose?
Give the missed dose as soon as you remember and then continue with your regular monthly schedule. Consistent dosing is especially important for heartworm prevention.
How do I choose the right Simparica Trio pack size?
Choose the pack that matches your dog's current body weight. Weigh your dog carefully, especially if they are close to a weight cutoff between sizes.
Can I buy Simparica Trio without a vet prescription?
Yes. Smartway ships genuine, Australian-registered stock, sold over the counter in Australia, without a vet prescription. Customers are responsible for ensuring their order complies with local import rules.
Can I buy Simparica Trio in Canada?
Yes. Smartway Pet Supplies ships genuine Simparica Trio to Canada with no vet prescription required. Standard shipping typically takes 7–14 business days, with free standard shipping on orders over $170 CAD. Express shipping is also available, arriving in 7–10 business days. Canadian customers are responsible for ensuring their order complies with local import regulations.