• Simparica Trio Chewables For Small Dogs 11.1-22lbs 5.1-10Kg Orange 3 Chews – front of pack
  • Simparica Trio Chewables For Small Dogs 11.1-22lbs 5.1-10Kg Orange – back of pack
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Simparica Trio Chewables For Small Dogs 11.1–22lbs (5.1-10Kg) Orange
$79.00 USD
$79.00 USD $79.00 USD
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  • ✔ Genuine branded product (sealed & in-date)
  • ✔ Ships from Australia with tracked delivery
  • ✔ No prescription required
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Title

Description

Simparica Trio for Small Dogs — Because One Chew Is Better Than Three Separate Treatments

Small dog owners know the challenge: a heartworm tablet, a flea treatment, tick prevention — keeping track of what's due and when. Simparica Trio eliminates that complexity entirely. One liver-flavored chew, given monthly, covers everything: heartworm disease, fleas, six species of ticks, Lyme disease prevention, roundworms, and hookworms. The Orange pack is sized for dogs 11.1–22 lbs (5.1–10 kg) — ideal for breeds like Beagles, Pugs, Cavaliers, Miniature Schnauzers, and Shih Tzus. Buy genuine Simparica Trio online from Smartway Pet Supplies — no vet prescription required, ships to the USA and Canada.

Full Spectrum Parasite Protection

Heartworm Prevention — One Dose, 100% Protection

Heartworm disease is diagnosed in every state across the US and is potentially fatal. The treatment for established heartworm infection is lengthy, expensive, and hard on the dog. Prevention is simple: one monthly Simparica Trio chew. Moxidectin prevents Dirofilaria immitis larvae from developing into adult worms. Veterinary clinical studies confirmed 100% heartworm protection with consistent monthly dosing.

Flea Treatment and Prevention — Fast and Thorough

Sarolaner starts killing adult fleas within 4 hours of dosing and achieves 100% flea kill by 8 hours. Critically, fleas die before they can lay eggs — preventing the life cycle from completing and stopping re-infestation in your home environment. For dogs with flea allergy dermatitis (FAD), a condition caused by sensitivity to flea saliva, consistent monthly flea prevention is the most effective management strategy available. Simparica Trio also prevents flea tapeworm infection by eliminating the flea vectors that carry Dipylidium caninum larvae.

Six Tick Species — The Most Comprehensive Tick Coverage Available

No other monthly oral combination preventive kills as many tick species as Simparica Trio. It provides proven, 30-day protection against:

  • Lone Star tick (Amblyomma americanum)
  • Gulf Coast tick (Amblyomma maculatum)
  • American dog tick (Dermacentor variabilis)
  • Black-legged (deer) tick (Ixodes scapularis)
  • Brown dog tick (Rhipicephalus sanguineus)
  • Asian longhorned tick (Haemaphysalis longicornis)

Ticks transmit serious diseases including Lyme disease, ehrlichiosis, anaplasmosis, and Rocky Mountain spotted fever. Monthly Simparica Trio eliminates ticks rapidly — at 48 hours post-dose, efficacy against existing infestations exceeds 98.9% for most species.

Proven Lyme Disease Prevention

Simparica Trio is the only combination monthly chewable clinically proven to help prevent infections that may cause Lyme disease, achieved by killing black-legged deer ticks before Borrelia burgdorferi bacteria can be transmitted. For dogs spending time in wooded or grassy areas in high-risk Lyme regions — particularly the Northeast, Great Lakes region, and Pacific Northwest — this is meaningful, specific protection.

Roundworms and Hookworms — Treated Monthly

Pyrantel treats and controls roundworm infections (Toxocara canis, Toxascaris leonina) and hookworm infections (Ancylostoma caninum, Uncinaria stenocephala). Hookworms are blood-feeders that can cause anaemia and weight loss in dogs. Roundworms are zoonotic and can be transmitted to humans. Monthly Simparica Trio treats existing infections and prevents re-infestation with each dose.

Active Ingredients

Simparica Trio was the first monthly chewable to combine three proven parasiticide classes:

  • Sarolaner (isoxazoline) — selectively inhibits the GABA-gated chloride channel in arthropods, causing paralysis and death in fleas and ticks within hours of contact with your dog's blood.
  • Moxidectin (macrocyclic lactone) — absorbed systemically after oral dosing; prevents heartworm larval development and provides activity against intestinal nematodes.
  • Pyrantel pamoate (tetrahydropyrimidine) — acts as a depolarizing neuromuscular blocker in intestinal roundworms and hookworms, causing paralysis and safe expulsion from the GI tract.

Dosing Information

  • One chew monthly for dogs weighing 11.1–22 lbs (5.1–10 kg)
  • Give with or without food
  • Safe for dogs and puppies from 8 weeks of age
  • Ensure the full chew is consumed
  • Administer year-round monthly for continuous protection

Helpful Guides

Shop All Simparica Trio Sizes

Frequently asked questions

Can I buy Simparica Trio without a prescription from Smartway?

Yes. Smartway Pet Supplies operates from Australia, where Simparica Trio can be sold without a prescription requirement. You can order online and have it shipped directly to your US or Canadian address without needing a vet's prescription.

Is Smartway's Simparica Trio the same as what my vet sells?

Yes — it is identical. Smartway sells only genuine, brand-name Zoetis Simparica Trio sourced from licensed Australian veterinary wholesalers. The product arrives in original, manufacturer-sealed packaging with the same formulation and efficacy as clinic or retail supply.

How much cheaper is Simparica Trio at Smartway vs. the vet?

Significantly. A 6-month supply of Simparica Trio at a US vet or through Chewy (with prescription) typically costs $180–$230 USD depending on size. Smartway's pricing is substantially lower — plus you avoid the cost and inconvenience of getting a prescription renewed.

How long does delivery take to the USA?

Standard shipping to the USA takes 7–14 business days from our Melbourne warehouse. Orders over $125 qualify for free standard shipping. Express delivery options are available at checkout.

Does Simparica Trio treat existing flea infestations or just prevent them?

Both. Simparica Trio kills existing adult fleas on your dog within 8 hours of the first dose, and prevents re-infestation by killing new fleas before they can lay eggs. For a heavy home infestation, an environmental flea spray may also help clear pupae from carpets and bedding faster.

My dog is on heartworm prevention — can I just switch to Simparica Trio?

Yes. If your dog is currently on a heartworm-only product like Heartgard, you can switch to Simparica Trio at the start of the next monthly dose cycle. Simparica Trio provides the same heartworm prevention plus flea, tick, and intestinal worm coverage in the same single monthly chew.

Is a vet check-in recommended before starting?

If your dog has been without heartworm prevention for more than a month or has never been tested, a heartworm test before starting is sensible. If your dog has a history of seizures, discuss with your vet first as sarolaner is an isoxazoline class drug.