The flea medication seems to be working keeping the fleas away. My cat isn’t itchy now!
Order arrived within 2 weeks
$0.00 USD
Zylkene
Couldn't load pickup availability
Zylkene is a calming supplement recommended by veterinarians. It helps dogs and cats manage stress and adapt to change. It also helps them cope with tough situations. Best of all, it does this without making them sleepy or sedated.
Zylkene is clinically proven and trusted around the world. It helps pets stay calm with a natural, gentle formula. This formula is safe for pets with sensitive stomachs.
Zylkene is formulated to help pets stay relaxed while remaining alert and responsive. It is:
Clinically proven to reduce stress without sedative side effects
Veterinarian recommended for anxiety related to travel, storms, fireworks, separation, and environmental changes
Made with natural ingredients, gentle on sensitive digestive systems
Lactose-free and preservative-free
Contains alpha-casozepine, a naturally occurring milk protein derived from cow’s milk
Alpha-casozepine helps control stress responses in the brain. It promotes calm behavior without changing your pet’s personality.
Zylkene is ideal for short-term or ongoing use during stressful or unfamiliar situations, including:
Vet visits, grooming appointments, boarding, or moving house can be overwhelming. Zylkene helps pets stay calm while adjusting to new surroundings—without sedation.
Fireworks, thunderstorms, car travel, and loud noises are common anxiety triggers. Zylkene supports relaxation while allowing pets to remain fully alert.
Whether welcoming guests, introducing a new baby, or adding another pet to the household, Zylkene helps pets adapt calmly to changes in their routine.
Zylkene is administered once daily and can be given whole or opened and mixed with food. It may be given during or after mealtime, making it simple to use even for fussy pets.
For best results, begin administration 1–2 days before a known stressful event. Some pets may benefit from starting 5–7 days in advance, as advised by a veterinarian.
| Zylkene Strength | Pet Body Weight | Recommended Daily Dose |
|---|---|---|
| 75 mg | Cats & dogs up to 10 lbs | 1 capsule per day |
| 75 mg | Cats & dogs 11–22 lbs | 2 capsules per day |
| 225 mg | Dogs 22–32 lbs | 1 capsule per day |
| 225 mg | Dogs 33–65 lbs | 2 capsules per day |
| 225 mg | Cats 22 lbs and over | 1 capsule per day |
| 450 mg | Dogs 33–65 lbs | 1 capsule per day |
| 450 mg | Dogs 66–132 lbs | 2 capsules per day |
Or as recommended by your veterinarian.
At Smartway Pet Supplies, we stock genuine Zylkene calming supplements with fast shipping and reliable customer support. Whether your pet needs help coping with temporary stress or ongoing anxiety, Zylkene provides a safe, non-drowsy solution backed by veterinary science.
Help your dog or cat face life’s challenges calmly with Zylkene—trusted, gentle, and effective.

Great on shipping. Very good price.
Excellent product
Even though I have to pay duties for this product to come to Canada 🇨🇦 it's still cheaper than getting it from the vet.
Plus having auto reorder is great except when you forget that it's set up and order the item again. 😀
Item shipped quickly, good communication!
The flea medication seems to be working keeping the fleas away. My cat isn’t itchy now!
Order arrived within 2 weeks