The flea medication seems to be working keeping the fleas away. My cat isn’t itchy now!
Order arrived within 2 weeks
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Simparica Trio
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Simparica Trio for Large Dogs provides complete, broad-spectrum parasite protection in one convenient monthly chew. This liver-flavored tablet is made for dogs that weigh 44.3 to 88 lbs. It helps protect against fleas, ticks, heartworm, and intestinal worms. You can get it in 3 and 6 Packs. This makes it easy to prevent parasites. It helps keep your dog healthy, active, and safe all year.
Designed specifically for larger breeds, Simparica Trio offers dependable protection in a simple monthly format. Its advanced triple-action formula quickly fights many parasites. This makes it an important part of your dog’s health routine.
Triple-action formula: Protects against fleas, ticks, heartworm, and intestinal worms.
Fast-acting flea elimination: Starts working within hours of administration.
Extended protection: Provides up to 35 days of defense against fleas and ticks.
Convenient monthly dosing: Keeps prevention simple and consistent.
Tasty beef-flavored chew: Easy for dogs to take without fuss.
Water-resistant: Remains effective after bathing or swimming.
Simparica Trio combines three active ingredients to provide comprehensive protection:
Sarolaner: Kills fleas and ticks by disrupting their nervous system.
Moxidectin: Prevents heartworm disease by eliminating developing larvae.
Pyrantel: Treats and controls intestinal worms, including roundworms and hookworms.
Together, these ingredients safeguard your dog’s overall health and protect against major internal and external parasites.
All-in-one parasite protection in a single chew
Rapid elimination of fleas and ticks
Prevents heartworm disease
Controls and treats roundworms and hookworms
No messy topicals or sprays required
Suitable for large dogs of various lifestyles
Simparica Trio is formulated for large dogs aged 8 weeks and older, weighing 44.3–88 lbs (20–40 kg). Always choose the right chew for your dog's weight. Talk to your veterinarian before use if your dog has health issues or takes other medications.
Choose the correct chew size for your dog’s weight.
Offer the chew directly as a treat or mix with food.
Ensure your dog consumes the full dose.
Administer once monthly on the same date for consistent protection.
For best results, give Simparica Trio with food to support optimal absorption.
Simparica Trio is generally well tolerated. Mild and temporary side effects can include:
Vomiting
Diarrhea
Lethargy
Reduced appetite
Follow your veterinarian’s dosage directions exactly. Do not exceed the recommended dose. If symptoms persist or worsen, seek veterinary advice promptly.
Simparica Trio for Large Dogs (Green) provides trusted, all-in-one parasite protection in a convenient monthly chew. You can choose from 3 and 6 Packs. This makes it easy to protect against fleas, ticks, heartworm, and intestinal worms. Keep your large dog healthy, happy, and parasite-free with dependable protection you can trust.
Brand: Simparica Trio
Animal Type: Dog
Weight Range: 44.3–88 lbs (20–40 kg)
Age Requirement: 8 weeks or older
Form: Oral Chew
Pack Sizes: 3 Chews or 6 Chews

Great on shipping. Very good price.
Excellent product
Even though I have to pay duties for this product to come to Canada 🇨🇦 it's still cheaper than getting it from the vet.
Plus having auto reorder is great except when you forget that it's set up and order the item again. 😀
Item shipped quickly, good communication!
The flea medication seems to be working keeping the fleas away. My cat isn’t itchy now!
Order arrived within 2 weeks