Revolution Plus and US Prescription Requirements
Revolution Plus is a monthly spot-on parasite treatment for cats made by Zoetis. In the United States, Revolution Plus is classified as a prescription-only veterinary medication. US vets and pharmacies require a valid prescription to dispense it.
However, in Australia, Revolution Plus is classified as an over-the-counter product by the APVMA — no prescription is required. This means Australian-registered retailers can sell and ship genuine Revolution Plus directly to US and Canadian cat owners without needing a vet script. For a full explanation of why Australian prices are lower, see why pet medications are cheaper from Australia.
What Makes Revolution Plus Different From Regular Revolution?
Original Revolution (selamectin) protects against fleas, heartworm, ear mites, roundworms, and hookworms. Revolution Plus adds sarolaner to the formula, extending tick coverage significantly. Where original Revolution has limited tick efficacy, Revolution Plus provides protection against black-legged ticks (deer ticks), American dog ticks, and Gulf Coast ticks.
For cat owners deciding between Revolution Plus and Bravecto Plus, see our full comparison: Revolution Plus vs Bravecto Plus for cats.
What Does Revolution Plus Treat?
Revolution Plus is one of the broadest-spectrum parasite treatments available for cats. A single monthly application protects against:
- Fleas (kills adults, eggs, and larvae)
- Ticks (black-legged, American dog, and Gulf Coast ticks)
- Heartworm disease (prevention)
- Ear mites
- Roundworms
- Hookworms
This makes Revolution Plus particularly valuable for multi-cat households or cats that spend any time outdoors.
How to Apply Revolution Plus
Revolution Plus is applied as a spot-on to the skin at the base of the cat's skull, between the shoulder blades. Part the fur to expose the skin, apply the entire tube in a single spot, and allow to dry. Do not bathe your cat or allow them to get wet within 2 hours of application.
Choosing the Right Revolution Plus Size for Your Cat
Revolution Plus is available in three weight ranges:
- Small cats and kittens: 2.8–5.5 lbs (1.25–2.5 kg) — Yellow
- Medium cats: 5.6–11 lbs (2.6–5 kg) — Orange
- Large cats: 11.1–22 lbs (5.1–10 kg) — Green
Revolution Plus is approved for use in kittens from 8 weeks of age weighing at least 2.8 lbs.
Is Personal Importation Legal?
Yes, under FDA personal importation guidelines, US residents may generally import pet medications from licensed overseas sources in limited quantities for personal use on their own animals. For the detailed legal explanation, see our article on whether it's legal to import pet medications from Australia.
Safety Information
Revolution Plus is considered safe for healthy cats and kittens. Side effects are uncommon but may include temporary hair loss at the application site, digestive upset, or lethargy. Keep cats away from other animals immediately after application until the product has dried. Do not use on cats that are sick, underweight, or debilitated without veterinary guidance.
Where to Buy Revolution Plus Without a Prescription
Smartway Pet Supplies stocks the full Revolution Plus cat range in all three weight sizes. Genuine Zoetis product, no prescription required, shipped directly to the USA and Canada.
Smartway Pet Supplies
Pet Care Specialist — Smartway Pet Supplies
A member of the Smartway team, writing practical guides to help US and Canadian pet owners choose the right parasite prevention products for their pets.
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