{"product_id":"heartgard-for-large-dogs-51-100-lbs-brown","title":"HeartGard Plus Chewables for Large Dogs 51–100 lbs (23–45 kg) – Brown","description":"\u003ch2\u003eHeartGard Plus Chewables for Large Dogs 51–100 lbs (23–45 kg) – Heartworm \u0026amp; Worm Prevention (Brown)\u003c\/h2\u003e\n\u003cp\u003eHeartGard Plus Chewables for Large Dogs deliver monthly heartworm prevention plus treatment for common intestinal worms in a soft, \u003cstrong\u003ereal beef\u003c\/strong\u003e chew most dogs eat like a treat. Specifically dosed for large dogs weighing \u003cstrong\u003e51–100 lbs (23–45 kg)\u003c\/strong\u003e, HeartGard Plus (Brown) protects against heartworm disease and treats roundworm and hookworm with one chew, once a month.\u003c\/p\u003e\n\u003ch3\u003eWhat HeartGard Plus Protects Against\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHeartworm:\u003c\/strong\u003e Prevents heartworm disease, transmitted by infected mosquitoes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoundworm:\u003c\/strong\u003e Treats and controls \u003cem\u003eToxocara canis\u003c\/em\u003e and \u003cem\u003eToxascaris leonina\u003c\/em\u003e infections.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHookworm:\u003c\/strong\u003e Treats and controls \u003cem\u003eAncylostoma caninum\u003c\/em\u003e and \u003cem\u003eUncinaria stenocephala\u003c\/em\u003e infections.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eNot covered:\u003c\/strong\u003e Fleas, ticks, tapeworm, or whipworm. For flea and tick protection, pair HeartGard Plus with NexGard, Bravecto, or a similar product.\u003c\/p\u003e\n\u003ch3\u003eWhy Large-Dog Owners Choose HeartGard Plus\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e#1 vet-recommended brand:\u003c\/strong\u003e The most-prescribed heartworm preventative in the US for decades.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReal beef chew:\u003c\/strong\u003e Made with real beef (not beef-flavored) — even fussy large dogs eat it eagerly.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCost-effective for large breeds:\u003c\/strong\u003e One monthly chew at a reasonable price — large-dog parasite protection adds up, and HeartGard Plus is well-priced for the value.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIntestinal worm coverage:\u003c\/strong\u003e Treats common roundworm and hookworm infections without a separate wormer.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRight size:\u003c\/strong\u003e The Brown pack is dosed for dogs 51–100 lbs — covers most adult Labradors, Golden Retrievers, German Shepherds, and similar large breeds.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHow HeartGard Plus Works\u003c\/h3\u003e\n\u003cp\u003eHeartGard Plus combines two active ingredients:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIvermectin\u003c\/strong\u003e targets immature heartworm larvae (microfilariae) before they can mature into adult heartworms — stopping the disease before it establishes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePyrantel pamoate\u003c\/strong\u003e paralyzes and clears adult roundworm and hookworm infections in the intestinal tract.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWho It’s For\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eLarge dogs weighing \u003cstrong\u003e51–100 lbs (23–45 kg)\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePuppies and adult dogs \u003cstrong\u003e6 weeks of age and older\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003eHealthy dogs — talk to your vet before use in herding breeds known to carry the MDR1 gene mutation\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eHow to Give HeartGard Plus\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003eGive \u003cstrong\u003eone chew per month\u003c\/strong\u003e, on the same date each month, year-round.\u003c\/li\u003e\n\u003cli\u003eOffer directly as a treat — most large dogs eagerly accept the real beef flavor.\u003c\/li\u003e\n\u003cli\u003eMake sure your dog chews and swallows the full chew.\u003c\/li\u003e\n\u003cli\u003eIf your dog is starting heartworm prevention for the first time at 7 months or older, your vet may recommend a heartworm test first.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch3\u003eSafety \u0026amp; Side Effects\u003c\/h3\u003e\n\u003cp\u003eHeartGard Plus is well tolerated by most dogs. Mild, short-lived side effects can include vomiting, diarrhea, lethargy, or reduced appetite.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImportant note for Collie \/ herding-breed owners:\u003c\/strong\u003e Some Collies, Australian Shepherds, Old English Sheepdogs, and related breeds carry the MDR1 gene mutation, which can make them sensitive to ivermectin at high doses. At the dose used in HeartGard Plus, the product is considered safe for these breeds — but if your dog has tested positive for MDR1, talk to your veterinarian before starting.\u003c\/p\u003e\n\u003ch3\u003eProduct Details\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBrand:\u003c\/strong\u003e HeartGard Plus (Boehringer Ingelheim)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFor:\u003c\/strong\u003e Dogs\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWeight range:\u003c\/strong\u003e 51–100 lbs (23–45 kg)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePack color:\u003c\/strong\u003e Brown\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Real-beef soft chew (oral)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eActive ingredients:\u003c\/strong\u003e Ivermectin + Pyrantel pamoate\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMinimum age:\u003c\/strong\u003e 6 weeks\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePack size:\u003c\/strong\u003e 6 chews (6 months of protection)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCoverage:\u003c\/strong\u003e Heartworm prevention + roundworm and hookworm treatment\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eFrequently Asked Questions\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eIs Brown the right pack for my Labrador, Golden Retriever, or German Shepherd?\u003c\/strong\u003e\u003cbr\u003eMost adult Labradors, Golden Retrievers, German Shepherds, Boxers, and similar large breeds fall within the Brown range (51–100 lbs). Weigh your dog to confirm — especially Labs and Goldens, which can exceed 100 lbs in some lines.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMy dog is over 100 lbs — what do I use?\u003c\/strong\u003e\u003cbr\u003eFor dogs over 100 lbs (typically Great Danes, Mastiffs, large Bernese Mountain Dogs, etc.), your vet may recommend combining HeartGard Plus packs to reach the correct ivermectin dose for body weight. Don’t do this without veterinary guidance — the exact combination depends on your dog’s weight.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIs this the same HeartGard Plus my vet sells?\u003c\/strong\u003e\u003cbr\u003eYes — it’s the same HeartGard Plus product manufactured by Boehringer Ingelheim, with the same active ingredients (ivermectin + pyrantel pamoate) at the same dosages. The only difference is you’re buying it directly from us, over the counter, without a prescription fee.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat’s the difference between HeartGard Plus and NexGard?\u003c\/strong\u003e\u003cbr\u003eHeartGard Plus prevents heartworm and treats intestinal worms. NexGard covers fleas and ticks. They’re complementary products that many dog owners use together for full parasite coverage. NexGard Spectra combines both into one chew if you prefer a single-product approach.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDo I need a prescription to buy HeartGard Plus?\u003c\/strong\u003e\u003cbr\u003eNo — SmartWay Pet Supplies ships HeartGard Plus \u003cstrong\u003eover the counter\u003c\/strong\u003e to customers across the US and Canada. No prescription or vet authorization required at checkout.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIs HeartGard Plus safe for Collies and herding breeds?\u003c\/strong\u003e\u003cbr\u003eAt the dose used in HeartGard Plus, the product is generally considered safe for Collies, Australian Shepherds, Shetland Sheepdogs, and other herding breeds. If your dog has tested positive for the MDR1 gene mutation, talk to your veterinarian before starting.\u003c\/p\u003e\n\u003ch3\u003eHelpful Links\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/heartgard-plus\"\u003eShop the full HeartGard Plus range\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/collections\/dog\"\u003eShop all dog parasite prevention\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eFast shipping across the US \u0026amp; Canada — no prescription required. Use only as directed on the packaging. Information provided for general reference; speak with your veterinarian for medical advice specific to your dog.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Heartgard Plus","offers":[{"title":"6 Chews","offer_id":47575446945945,"sku":"HEA-DG-HEAR-152","price":74.97,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0635\/9590\/5177\/files\/heartgard-x6-retail-pack-shot-angle-23-45kg-large_1.jpg?v=1713650771","url":"https:\/\/www.smartwaypetsupplies.com\/products\/heartgard-for-large-dogs-51-100-lbs-brown","provider":"Smartway Pet Supplies","version":"1.0","type":"link"}